In this episode of Rebel Cast, host Marco Propersi, along with co-hosts Steve Hochman and Kim Baldino, delve into the practice and importance of street medicine—the direct delivery of healthcare to homeless and unsheltered individuals. Special guests Dr. Jim O'Connell, a pioneer of street medicine, and Dr. Ed Egan, a recent street medicine fellowship graduate, share their experiences and insights on serving this vulnerable population. They discuss the origins, scope, and challenges of street medicine, the ethical dilemmas faced, and the profound impact of building trust and community with patients. The conversation underscores the necessity of integrating street medicine with mainstream healthcare systems and emphasizes that small acts of kindness and persistence can significantly improve the lives of those experiencing homelessness.

In this episode of RebelCast, host Dr. Marco Propersi and guest Dr. Lynnsey Moss discuss the comparative study of piperacillin-tazobactam versus cefepime in the treatment of undifferentiated sepsis. They discuss a recent retrospective cohort study which examines 90-day mortality rates is sepsis patients treated with these antibiotics. The researchers explore the role of anti-anaerobic coverage and its potential for disrupting the gut microbiome. Key points discussed include the method of instrumental variable analysis, the validity of study findings, and a comparison with the ACORN trial. The episode concludes with a cautious stance on changing clinical practice based on these findings.